Department of Biotechnology and Bioinformatics
Permanent URI for this community
Browse
Browsing Department of Biotechnology and Bioinformatics by Supervisor "Prakash Babu, P"
Results Per Page
Sort Options
-
ItemClinical and therapeutic significance of epithelial to mesenchymal transition (EMT) like process in glioma(University of Hyderabad, 2018-09-30) Deepak Babu ; Prakash Babu, P
-
ItemCognitive dyfunction in experimental cerehral Malaria : possible role of neurodegeneration and morphological alterations(University of Hyderabad, 2019-05-31) Praveen Kumar, Simhadri ; Prakash Babu, P
-
ItemIdentification of possible diagnostic and prognostic markers in human astrocytoma and targeting JNK, NF-kB signaling in glioma(UNIVERSITY OF HYDERABAD, 2015-04-30) Khamushavalli, G ; Prakash Babu, P
-
ItemRettospective clinical analysis and pathological singificance of biomarkers for astrocytoma progression(University of Hyderabad, 2017-06-01) Ravindra Pramod, Deshpande ; Prakash Babu, PAstrocytoma’s are the most common malignancies of the brain. World Health Organization (WHO) has classified astrocytoma in four grades (Grade I- pilocytic astrocytoma, Grade II- diffuse astrocytoma, Grade III- anaplastic astrocytoma and Grade IV- glioblastoma multiforme) on account of cellularity, nuclear polymorphism, mitotic index, microvascular proliferation and extent of necrosis [1]. However recent scheme of classification based on the co-expression modules around most mutated gene such as receptor tyrosine kinases are proposed to accurately assign prognosis in astrocytoma cases[2]. Grade IV astrocytoma also referred as glioblastoma multiformae (GBM), are the most aggressive primary tumours with worst prognosis and account for nearly 60% of malignant gliomas [3-5]. The overall prognosis for malignant glial tumours have not changed significantly since 1980 despite of advancements in course of diagnosis and mode of treatment