Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions
Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions
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Date
2007-01-04
Authors
Basavaiah, Deevi
Reddy, Kanumuri Ramesh
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Abstract
(Chemical Equation Presented) A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented. © 2007 American Chemical Society.
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Organic Letters. v.9(1)