Pd(II)-catalyzed ortho -C-H oxidation of arylacetic acid derivatives: Synthesis of benzofuranones
Pd(II)-catalyzed ortho -C-H oxidation of arylacetic acid derivatives: Synthesis of benzofuranones
| dc.contributor.author | Rit, Raja K. | |
| dc.contributor.author | Yadav, M. Ramu | |
| dc.contributor.author | Sahoo, Akhila K. | |
| dc.date.accessioned | 2022-03-27T08:34:09Z | |
| dc.date.available | 2022-03-27T08:34:09Z | |
| dc.date.issued | 2014-02-07 | |
| dc.description.abstract | Pd(II)-catalyzed ortho-C-H acetoxylation of arylacetic acid derivatives is demonstrated with the aid of a novel S-methyl-S-2-pyridylsulfoximine (MPyS) directing group (DG). The α-mono- and α-unsubstituted arylacetic acid derivatives were readily employed in the ortho-C-H acetoxylations. The oxidation products are hydrolyzed, and the MPyS-DG is easily recovered, providing ready access to o-hydroxyarylacetic acids. 3-Mono- and 3-unsubstituted benzofuranones are synthesized from o-hydroxyarylacetic acids. © 2014 American Chemical Society. | |
| dc.identifier.citation | Organic Letters. v.16(3) | |
| dc.identifier.issn | 15237060 | |
| dc.identifier.uri | 10.1021/ol403699d | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/ol403699d | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/10882 | |
| dc.title | Pd(II)-catalyzed ortho -C-H oxidation of arylacetic acid derivatives: Synthesis of benzofuranones | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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