The α/β-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering
The α/β-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering
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Date
2010-08-16
Authors
Kourist, Robert
Jochens, Helge
Bartsch, Sebastian
Kuipers, Remko
Padhi, Santosh Kumar
Gall, Markus
Böttcher, Dominique
Joosten, Henk Jan
Bornscheuer, Uwe T.
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Abstract
(Figure Presented) Aligning the haystack to expose the needle: The 3DM method was used to generate a comprehensive database of the α/β- hydrolase fold enzyme superfamily. This database facilitates the analysis of structure-function relationships and enables novel insights into this superfamily to be made. In addition high-quality libraries for protein engineering can be easily designed. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.
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Keywords
3DM,
Alpha/beta hydrolase fold,
Bioinformatics,
Databases,
Protein engineering
Citation
ChemBioChem. v.11(12)