Oxidative C < inf > sp3 < /inf > -H functionalization of 2-methylazaarenes: A practical synthesis of 2-azaarenyl-benzimidazoles and benzothiazoles

dc.contributor.author	Yaragorla, Srinivasarao
dc.contributor.author	Vijaya Babu, P.
dc.date.accessioned	2022-03-27T08:49:43Z
dc.date.available	2022-03-27T08:49:43Z
dc.date.issued	2017-01-01
dc.description.abstract	Oxidative Csp3-H functionalization of 2-methylazaarenes using I2-DMSO in open flask has been described first time for the synthesis of 2-azaarenyl benzimidazoles and 2-azaarenyl benzothiazoles. Generally, methyl group of 2-methylazaarenes serves as a carbon nucleophile and in this work the methyl group served as electrophilic carbon (umpolung!) and condensed with o-Phenylenediamine and 2-aminothiophenol to furnish the corresponding benzimidazoles and benzothiazoles in high yields with good substrate scope and functional group tolerance.
dc.identifier.citation	Tetrahedron Letters. v.58(19)
dc.identifier.issn	00404039
dc.identifier.uri	10.1016/j.tetlet.2017.04.007
dc.identifier.uri	https://www.sciencedirect.com/science/article/abs/pii/S0040403917304276
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/11885
dc.subject	2-Methylazaarenes
dc.subject	Benzimidazoles
dc.subject	Benzothiazoles
dc.subject	Iodine catalyzed
dc.subject	Oxidative functionalization
dc.title	Oxidative C < inf > sp3 < /inf > -H functionalization of 2-methylazaarenes: A practical synthesis of 2-azaarenyl-benzimidazoles and benzothiazoles
dc.type	Journal. Article
dspace.entity.type

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