Ru-Catalyzed One-Pot Diannulation of Heteroaryls: Direct Access to π-Conjugated Polycyclic Amides

dc.contributor.author Shankar, Majji
dc.contributor.author Ghosh, Koushik
dc.contributor.author Mukherjee, Kallol
dc.contributor.author Rit, Raja K.
dc.contributor.author Sahoo, Akhila K.
dc.date.accessioned 2022-03-27T09:56:49Z
dc.date.available 2022-03-27T09:56:49Z
dc.date.issued 2016-12-16
dc.description.abstract A novel Ru-catalyzed oxidative double annulation of heteroarenes with symmetrical and unsymmetrical alkynes is reported. A general method for the unsymmetrical annulation of heteroarenes with two distinct alkynes is showcased for the first time. Methylphenyl sulfoximine (MPS) plays an important role in the annulations of heteroarenes and allows the construction of structurally complex π-conjugated heteroarene-fused polycyclic amide skeletons via the formation of multiple C-C and C-N bonds in a single operation. The reaction exhibits excellent substrate scope and tolerates a wide range of functional groups.
dc.identifier.citation Organic Letters. v.18(24)
dc.identifier.issn 15237060
dc.identifier.uri 10.1021/acs.orglett.6b03314
dc.identifier.uri https://pubs.acs.org/doi/10.1021/acs.orglett.6b03314
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/13463
dc.title Ru-Catalyzed One-Pot Diannulation of Heteroaryls: Direct Access to π-Conjugated Polycyclic Amides
dc.type Journal. Article
dspace.entity.type
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