Cyclocarbonylation-Iodination of terminal alkynes with ketones and ICl via 1,2-migration

dc.contributor.author	Mahesh Kumar, K.
dc.contributor.author	Khan, Tabassum
dc.contributor.author	Almansour, Abdulrahman I.
dc.contributor.author	Arumugam, Natarajan
dc.contributor.author	Yaragorla, Srinivasarao
dc.date.accessioned	2022-03-27T08:49:03Z
dc.date.available	2022-03-27T08:49:03Z
dc.date.issued	2020-09-24
dc.description.abstract	A simple, three-component, one-pot, room-temperature reaction of cyclocarbonylation-iodination is developed from terminal alkynes, ketones, and ICl. The reaction proceeds through the formation of 3°-propargyl alcohols and a subsequent 1,2-shift lead to the formation of β-iodo-α,β-unsaturated cyclic and acyclic ketones in good yields. In the case of cyclic ketones, the products are obtained with ring expansion.
dc.identifier.citation	Tetrahedron Letters. v.61(39)
dc.identifier.issn	00404039
dc.identifier.uri	10.1016/j.tetlet.2020.152374
dc.identifier.uri	https://www.sciencedirect.com/science/article/abs/pii/S0040403920308522
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/11858
dc.subject	1,2-Migration
dc.subject	Alkynes
dc.subject	Ketones
dc.subject	Propargyl alcohols
dc.subject	Ring expansion
dc.title	Cyclocarbonylation-Iodination of terminal alkynes with ketones and ICl via 1,2-migration
dc.type	Journal. Article
dspace.entity.type

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