Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF < inf > 4 < /inf > )
Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF < inf > 4 < /inf > )
| dc.contributor.author | Naveen, Naganaboina | |
| dc.contributor.author | Balamurugan, Rengarajan | |
| dc.date.accessioned | 2022-03-27T08:39:11Z | |
| dc.date.available | 2022-03-27T08:39:11Z | |
| dc.date.issued | 2017-01-01 | |
| dc.description.abstract | A facile method for the synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols from tertiary propargyl alcohols under electrophilic fluorination conditions using F-TEDA-BF4 has been presented. The products bear pharmaceutically important α-fluoro ketone, gem-diaryl and fluorohydrin moieties in the same molecule. Interestingly, this catalyst free protocol results in monofluorination. | |
| dc.identifier.citation | Organic and Biomolecular Chemistry. v.15(9) | |
| dc.identifier.issn | 14770520 | |
| dc.identifier.uri | 10.1039/c7ob00140a | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=C7OB00140A | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/11372 | |
| dc.title | Catalyst free synthesis of α-fluoro-β-hydroxy ketones/α-fluoro-ynols via electrophilic fluorination of tertiary propargyl alcohols using Selectfluor™ (F-TEDA-BF < inf > 4 < /inf > ) | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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