Total synthesis of the marine alkaloid mansouramycin D

dc.contributor.author Prakash, K. S.
dc.contributor.author Nagarajan, Rajagopal
dc.date.accessioned 2022-03-27T08:40:00Z
dc.date.available 2022-03-27T08:40:00Z
dc.date.issued 2014-01-03
dc.description.abstract Mansouramycin D, a cytotoxic alkaloid was isolated from a marine Streptomyces sp. in 2009. The first, simple, and concise route to the total synthesis of Mansouramycin D is reported. The core structure of the isoquinoline ring has been constructed from iminoannulation of 2-alkynylbenzaldehyde followed by oxidation/deprotection and oxidative amination via a three-step sequence from easily accessible starting materials. © 2013 American Chemical Society.
dc.identifier.citation Organic Letters. v.16(1)
dc.identifier.issn 15237060
dc.identifier.uri 10.1021/ol4032396
dc.identifier.uri https://pubs.acs.org/doi/10.1021/ol4032396
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/11424
dc.title Total synthesis of the marine alkaloid mansouramycin D
dc.type Journal. Article
dspace.entity.type
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