An expedient, facile and simple one-pot synthesis of 2-methylenealkanoates and alkanenitriles from the Baylis-Hillman bromides in aqueous media.

dc.contributor.author Basavaiah, Deevi
dc.contributor.author Reddy, Kanumuri Ramesh
dc.contributor.author Kumaragurubaran, Nagaswamy
dc.date.accessioned 2022-03-27T09:02:03Z
dc.date.available 2022-03-27T09:02:03Z
dc.date.issued 2007-01-01
dc.description.abstract This protocol is for an expedient and operationally simple one-pot synthesis of 2-methylenealkanoates and alkanenitriles in high yields from the corresponding Baylis-Hillman bromides. The reaction proceeds via the successive treatment with 1,4-diazabicyclo(2.2.2)octane (DABCO) for 15 min and sodium borohydride for 15 min in aqueous media [tetrahydrofuran (THF):H2O (1:1)] at room temperature.
dc.identifier.citation Nature protocols. v.2(11)
dc.identifier.uri 10.1038/nprot.2007.369
dc.identifier.uri http://www.nature.com/articles/nprot.2007.369
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/12302
dc.title An expedient, facile and simple one-pot synthesis of 2-methylenealkanoates and alkanenitriles from the Baylis-Hillman bromides in aqueous media.
dc.type Journal. Article
dspace.entity.type
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