Thioarylative Radical Cyclization of Yne-Dienone

dc.contributor.author	Mallick, Rajendra K.
dc.contributor.author	Dutta, Shubham
dc.contributor.author	Vanjari, Rajeshwer
dc.contributor.author	Voituriez, Arnaud
dc.contributor.author	Sahoo, Akhila K.
dc.date.accessioned	2022-03-27T09:45:32Z
dc.date.available	2022-03-27T09:45:32Z
dc.date.issued	2019-08-16
dc.description.abstract	We herein demonstrated a N-hydroxyphthalimide (NHPI)-mediated chemo- and regioselective radical cyclization of yne-dienone with thiols to construct 3-thioaryl bearing [6,6]-fused dihydrochromenone derivatives. This transformation tolerates common functional groups and has broad scope. The reaction proceeds via the attack of a thioaryl radical to alkyne over the activated Michael acceptor. The TEMPO quenching experiment suggests the involvement of a radical intermediate. Synthetic versatility of 3-thioaryldihydrochromenones is also showcased.
dc.identifier.citation	Journal of Organic Chemistry. v.84(16)
dc.identifier.issn	00223263
dc.identifier.uri	10.1021/acs.joc.9b01445
dc.identifier.uri	https://pubs.acs.org/doi/10.1021/acs.joc.9b01445
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/13274
dc.title	Thioarylative Radical Cyclization of Yne-Dienone
dc.type	Journal. Article
dspace.entity.type

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