First example of electrophile induced Baylis-Hillman reaction: A novel facile one-pot synthesis of indolizine derivatives
First example of electrophile induced Baylis-Hillman reaction: A novel facile one-pot synthesis of indolizine derivatives
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Date
2003-01-01
Authors
Basavaiah, Deevi
Jaganmohan Rao, Anumolu
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Abstract
Treatment of pyridine-2-carboxaldehyde with activated alkenes such as alkyl vinyl ketones and cyclic enones in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides a novel facile one-pot synthesis of indolizine derivatives, thus for the first time describing an electrophile induced Baylis-Hillman reaction. © 2003 The Royal Society of Chemistry.
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Chemical Communications. v.3(5)