Stereoselective synthesis of sugar fused β-disubstituted γ-butyro-lactones: C-spiro-glycosides from 1,2-cyclopropanecarboxylated sugars
Stereoselective synthesis of sugar fused β-disubstituted γ-butyro-lactones: C-spiro-glycosides from 1,2-cyclopropanecarboxylated sugars
| dc.contributor.author | Ramu Sridhar, Perali | |
| dc.contributor.author | Seshadri, Kalapati | |
| dc.contributor.author | Madhusudhan Reddy, Gadi | |
| dc.date.accessioned | 2022-03-27T08:37:36Z | |
| dc.date.available | 2022-03-27T08:37:36Z | |
| dc.date.issued | 2012-12-12 | |
| dc.description.abstract | A stereoselective methodology was developed for the construction of C-spiro-glycosides in two steps involving bromonium ion activated solvolytic ring opening of sugar derived 1,2-cyclopropanecarboxylates followed by a one-pot dehydrohalogenation, intramolecular hetero-Michael addition (IHMA) and ester hydrolysis. The obtained spirocyclic lactols were further converted to enantiomerically pure spirolactones. © 2012 The Royal Society of Chemistry. | |
| dc.identifier.citation | Chemical Communications. v.48(5) | |
| dc.identifier.issn | 13597345 | |
| dc.identifier.uri | 10.1039/c1cc16417a | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=C1CC16417A | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/11265 | |
| dc.title | Stereoselective synthesis of sugar fused β-disubstituted γ-butyro-lactones: C-spiro-glycosides from 1,2-cyclopropanecarboxylated sugars | |
| dc.type | Journal. Article | |
| dspace.entity.type |
Files
License bundle
1 - 1 of 1