Simple and one-pot synthesis of tri and tetracyclic frameworks containing [1,8]naphthyridin-2-one moiety from the Baylis-Hillman adducts
Simple and one-pot synthesis of tri and tetracyclic frameworks containing [1,8]naphthyridin-2-one moiety from the Baylis-Hillman adducts
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Date
2010-02-06
Authors
Basavaiah, Deevi
Reddy, Kanumuri Ramesh
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Abstract
A facile synthesis of tri and tetracyclic frameworks containing [1,8]naphthyridin-2-one skeleton from the Baylis-Hillman alcohols via the Johnson-Claisen rearrangement, followed by the treatment with Fe/AcOH in simple one-pot multi-step process is described. © 2009 Elsevier Ltd. All rights reserved.
Description
Keywords
[1,8]naphthyridin-2-ones,
Baylis-Hillman reaction,
Cyclization,
DABCO,
Fe/AcOH,
Johnson-Claisen rearrangement,
Reduction
Citation
Tetrahedron. v.66(6)