Diastereoselective reductive N-alkylation of (R,R)-trans-1,2-diaminocyclohexane with prochiral ketones using the Ti(O < sup > i < /sup > Pr) < inf > 4 < /inf > /NaBH < inf > 4 < /inf > system
Diastereoselective reductive N-alkylation of (R,R)-trans-1,2-diaminocyclohexane with prochiral ketones using the Ti(O < sup > i < /sup > Pr) < inf > 4 < /inf > /NaBH < inf > 4 < /inf > system
| dc.contributor.author | Dalai, Manasi | |
| dc.contributor.author | Periasamy, Mariappan | |
| dc.date.accessioned | 2022-03-27T09:07:50Z | |
| dc.date.available | 2022-03-27T09:07:50Z | |
| dc.date.issued | 2009-06-19 | |
| dc.description.abstract | A simple and convenient one-pot method for the reductive N-alkylation of (R,R)-trans-1,2-diaminocyclohexane by prochiral ketones using a Ti(OiPr)4/NaBH4 system to obtain the corresponding alkyl amine derivatives in 76-95% yields with good diastereoselectivity (dr = up to 23:1:1) is reported. © 2009 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron Asymmetry. v.20(11) | |
| dc.identifier.issn | 09574166 | |
| dc.identifier.uri | 10.1016/j.tetasy.2009.05.004 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0957416609003632 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12463 | |
| dc.title | Diastereoselective reductive N-alkylation of (R,R)-trans-1,2-diaminocyclohexane with prochiral ketones using the Ti(O < sup > i < /sup > Pr) < inf > 4 < /inf > /NaBH < inf > 4 < /inf > system | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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