Toward understanding the scope of Baylis-Hillman reaction: Synthesis of 3-(2- hydroxyphenyl)indolin-2-ones and polycyclic fused furans

dc.contributor.author Basavaiah, Deevi
dc.contributor.author Roy, Suparna
dc.contributor.author Das, Utpal
dc.date.accessioned 2022-03-27T09:01:30Z
dc.date.available 2022-03-27T09:01:30Z
dc.date.issued 2010-07-24
dc.description.abstract A facile one-pot synthesis of 3-(2-hydroxyphenyl)indolin-2-ones has been developed via the TiCl4-me- diated Baylis-Hillman (B-H) reaction of N-substituted isatins and cyclohex-2-enone, followed by treatment of the in situ generated B-H alcohols with aq HBr. Baylis-Hillman reaction of aromatic cyclic 1, 2-diones with cycloalk-2-enones under the influence of TiCl4 has been successfully performed and the resulting Baylis-Hillman adducts have been conveniently transformed into pentacyclic and hexacyclic fused furan derivatives. © 2010 Elsevier Ltd. All rights reserved.
dc.identifier.citation Tetrahedron. v.66(30)
dc.identifier.issn 00404020
dc.identifier.uri 10.1016/j.tet.2010.05.087
dc.identifier.uri https://www.sciencedirect.com/science/article/abs/pii/S0040402010008410
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/12286
dc.subject 2-diones
dc.subject 3-(2-Hydroxyphenyl)indolin-2-ones
dc.subject Baylis-Hillman reaction
dc.subject Cyclic 1
dc.subject Cycloalk-2-enones
dc.subject Polycyclic fused furans
dc.title Toward understanding the scope of Baylis-Hillman reaction: Synthesis of 3-(2- hydroxyphenyl)indolin-2-ones and polycyclic fused furans
dc.type Journal. Article
dspace.entity.type
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