Enantioselective synthesis using crude enzymes

Abstract

Chiral trans-2-aryloxycyclohexan-l-ols, trans-2-alkoxy cyclohexan-l-ols, trans-2-arylcyclohexan-l-ols, homoallyl alcohols, 1-aryl-l-alkanols, 1,2-diphenylethane-l,2-diol are prepared in high optical purities via enantioselective hydrolysis of acetates of the corresponding racemic alcohols using crude enzymes such as pig liver acetone powder (PLAP), goat liver acetone powder (GLAP), chicken liver acetone powder (CLAP) and bovine liver acetone powder (BLAP). © 1992, IUPAC