Synthesis of chiral α-aryl-α-hydroxyacetic acids: Substituent effects in pig liver acetone powder (PLAP) induced enantioselective hydrolysis
Synthesis of chiral α-aryl-α-hydroxyacetic acids: Substituent effects in pig liver acetone powder (PLAP) induced enantioselective hydrolysis
| dc.contributor.author | Basavaiah, Deevi | |
| dc.contributor.author | Rama Krishna, Peddinti | |
| dc.date.accessioned | 2022-03-27T09:04:23Z | |
| dc.date.available | 2022-03-27T09:04:23Z | |
| dc.date.issued | 1995-02-20 | |
| dc.description.abstract | Pig liver acetone powder (PLAP) catalyzed hydrolysis of alkyl α-acetoxy-α-arylacetates produces alkyl (S)-α-aryl-α-hydroxyacetates in 23-80% enantiomeric purities. Enantioselectivity is dependent on the ester group of O-acetylmandelates. Substitution on the aromatic ring results in inferior selectivities. Only acetate group is hydrolyzed by PLAP while the ester functionality is found to be completely intact. © 1995. | |
| dc.identifier.citation | Tetrahedron. v.51(8) | |
| dc.identifier.issn | 00404020 | |
| dc.identifier.uri | 10.1016/0040-4020(94)01105-9 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/0040402094011059 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12369 | |
| dc.title | Synthesis of chiral α-aryl-α-hydroxyacetic acids: Substituent effects in pig liver acetone powder (PLAP) induced enantioselective hydrolysis | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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