Regiospecific formal [3 + 2] annulation of: Tert -propargyl alcohols with acyclic 1,3-diketones via the cycloisomerization of homoallenyl ketones
Regiospecific formal [3 + 2] annulation of: Tert -propargyl alcohols with acyclic 1,3-diketones via the cycloisomerization of homoallenyl ketones
| dc.contributor.author | Yaragorla, Srinivasarao | |
| dc.contributor.author | Rajesh, P. | |
| dc.date.accessioned | 2022-03-27T08:49:24Z | |
| dc.date.available | 2022-03-27T08:49:24Z | |
| dc.date.issued | 2019-01-01 | |
| dc.description.abstract | A one-pot, regiospecific synthesis of dihydrofurans bearing a quaternary centre and tetrasubstituted furans is developed from the formal [3 + 2] annulation of tert-propargyl alcohols and 1,3-diketones under Ca(ii)/DBU conditions. The reaction proceeds through the S N 2 I mechanism to form homoallenyl ketone and a subsequent cycloisomerization to yield novel and new chemical entities of privileged scaffolds. | |
| dc.identifier.citation | Organic and Biomolecular Chemistry. v.17(7) | |
| dc.identifier.issn | 14770520 | |
| dc.identifier.uri | 10.1039/c8ob02158a | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=C8OB02158A | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/11872 | |
| dc.title | Regiospecific formal [3 + 2] annulation of: Tert -propargyl alcohols with acyclic 1,3-diketones via the cycloisomerization of homoallenyl ketones | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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