Palladium-Catalyzed Tandem-Cyclization of Functionalized Ynamides: An Approach to Benzosultams

dc.contributor.author	Siva Reddy, Alla
dc.contributor.author	Siva Kumari, A. Leela
dc.contributor.author	Saha, Soumen
dc.contributor.author	Kumara Swamy, K. C.
dc.date.accessioned	2022-03-27T09:48:47Z
dc.date.available	2022-03-27T09:48:47Z
dc.date.issued	2016-05-19
dc.description.abstract	A palladium-catalyzed tandem-cyclization of functionalized ynamides to afford a wide range of hetero-substituted benzosultams (1,2-benzothiazine 1,1-dioxides) has been achieved. Medicinally useful compounds like nortriptyline and eugenol could also be used as nucleophiles. Base has a significant effect in the cyclization process, depending on the nucleophile source used. DFT studies suggest that the reaction involves a [Pd(II)]–[Pd(0)]–[Pd(II)] cycle. Structures of key products were proven by X-ray crystallography. (Figure presented.).
dc.identifier.citation	Advanced Synthesis and Catalysis. v.358(10)
dc.identifier.issn	16154150
dc.identifier.uri	10.1002/adsc.201500854
dc.identifier.uri	https://onlinelibrary.wiley.com/doi/10.1002/adsc.201500854
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/13331
dc.subject	benzosultams
dc.subject	cyclization
dc.subject	palladium catalysis
dc.subject	ynamides
dc.title	Palladium-Catalyzed Tandem-Cyclization of Functionalized Ynamides: An Approach to Benzosultams
dc.type	Journal. Article
dspace.entity.type

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