Amine-catalyzed direct self Diels-Alder reactions of α,β-unsaturated ketones in water: Synthesis of pro-chiral cyclohexanones

dc.contributor.author	Ramachary, D. B.
dc.contributor.author	Chowdari, Naidu S.
dc.contributor.author	Barbas, Carlos F.
dc.date.accessioned	2022-03-27T09:43:07Z
dc.date.available	2022-03-27T09:43:07Z
dc.date.issued	2002-09-16
dc.description.abstract	Amine-catalyzed direct self Diels-Alder reactions of α,β-unsaturated ketones have been developed. (S)-1-(2-Pyrrolidinyl-methyl)pyrrolidine, L-proline and pyrrolidine catalyzed the reaction of α,β-unsaturated ketones to provide cyclohexanone derivatives with good yield (up to 80%) in a single step via in situ-generation of 2-amino-1,3-butadienes and iminium ion-activated enones. Pro-chiral cyclohexanones were selectively prepared with pyrrolidine catalysis in water. © 2002 Published by Elsevier Science Ltd.
dc.identifier.citation	Tetrahedron Letters. v.43(38)
dc.identifier.issn	00404039
dc.identifier.uri	10.1016/S0040-4039(02)01500-9
dc.identifier.uri	https://www.sciencedirect.com/science/article/abs/pii/S0040403902015009
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/13231
dc.subject	Amines
dc.subject	Aqueous media
dc.subject	Cyclohexanones
dc.subject	Diels-Alder reactions
dc.subject	Enamines
dc.subject	Imines
dc.subject	Organocatalysis
dc.title	Amine-catalyzed direct self Diels-Alder reactions of α,β-unsaturated ketones in water: Synthesis of pro-chiral cyclohexanones
dc.type	Journal. Article
dspace.entity.type

Now showing 1 - 1 of 1