Gold(I)-catalyzed 6-endo-dig hydrative cyclization of an alkyne-tethered ynamide: Access to 1,6-dihydropyridin-2(3H)ones
Gold(I)-catalyzed 6-endo-dig hydrative cyclization of an alkyne-tethered ynamide: Access to 1,6-dihydropyridin-2(3H)ones
| dc.contributor.author | Ghosh, Nayan | |
| dc.contributor.author | Nayak, Sanatan | |
| dc.contributor.author | Sahoo, Akhila K. | |
| dc.date.accessioned | 2022-03-27T08:34:19Z | |
| dc.date.available | 2022-03-27T08:34:19Z | |
| dc.date.issued | 2013-07-15 | |
| dc.description.abstract | Hydrate your chemistry! Hydrative cyclization of 5-yne-ynamides in the presence of Echavarren's catalyst and p-toluenesulphonic acid (PTSA)×H2O at room temperature affords an array of 1,6-dihydropyridin-2(3H)one derivatives. Isomerization, epoxidation, and hydrogenation of the double bond and insertion of an extended π-conjugate system into the pyridinone skeleton have been successfully accomplished (see scheme; Ts=tosyl). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | |
| dc.identifier.citation | Chemistry - A European Journal. v.19(29) | |
| dc.identifier.issn | 09476539 | |
| dc.identifier.uri | 10.1002/chem.201301599 | |
| dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/chem.201301599 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/10915 | |
| dc.subject | gold catalysis | |
| dc.subject | heterocycles | |
| dc.subject | hydrative cyclization | |
| dc.subject | pyridinones | |
| dc.subject | yne-ynamides | |
| dc.title | Gold(I)-catalyzed 6-endo-dig hydrative cyclization of an alkyne-tethered ynamide: Access to 1,6-dihydropyridin-2(3H)ones | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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