Direct amino acid-catalyzed cascade reductive alkylation of arylacetonitriles: High-yielding synthesis of ibuprofen analogs
Direct amino acid-catalyzed cascade reductive alkylation of arylacetonitriles: High-yielding synthesis of ibuprofen analogs
| dc.contributor.author | Ramachary, Dhevalapally B. | |
| dc.contributor.author | Shiva Prasad, M. | |
| dc.date.accessioned | 2022-03-27T09:40:49Z | |
| dc.date.available | 2022-03-27T09:40:49Z | |
| dc.date.issued | 2010-10-06 | |
| dc.description.abstract | A novel approach for a one-pot, three-component reductive alkylation (TCRA) reaction of arylacetonitriles-containing electron-withdrawing groups with aldehydes/ketones and 1,4-dihydropyridine via iminium-catalysis has been developed. Many TCRA reaction products have direct applications in agricultural and pharmaceutical chemistry. © 2010 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron Letters. v.51(40) | |
| dc.identifier.issn | 00404039 | |
| dc.identifier.uri | 10.1016/j.tetlet.2010.07.131 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0040403910013377 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/13189 | |
| dc.subject | Amino acids | |
| dc.subject | Cascade reactions | |
| dc.subject | Ibuprofen analogs | |
| dc.subject | Organocatalysis | |
| dc.subject | TCRA reactions | |
| dc.title | Direct amino acid-catalyzed cascade reductive alkylation of arylacetonitriles: High-yielding synthesis of ibuprofen analogs | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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