Identification and characterization of a major cell wall-associated iron-regulated envelope protein (Irep-28) in Mycobacterium tuberculosis
Identification and characterization of a major cell wall-associated iron-regulated envelope protein (Irep-28) in Mycobacterium tuberculosis
| dc.contributor.author | Yeruva, Veena C. | |
| dc.contributor.author | Duggirala, Sridevi | |
| dc.contributor.author | Lakshmi, V. | |
| dc.contributor.author | Kolarich, Daniel | |
| dc.contributor.author | Altmann, Friedrich | |
| dc.contributor.author | Sritharan, Manjula | |
| dc.date.accessioned | 2022-03-27T00:59:13Z | |
| dc.date.available | 2022-03-27T00:59:13Z | |
| dc.date.issued | 2006-10-01 | |
| dc.description.abstract | Iron limitation and the expression of mycobactin and carboxymycobactin by Mycobacterium tuberculosis are known. Here, we report how iron regulated the coordinate expression of these two siderophores and a 28-kDa cell wall-associated iron-regulated protein (Irep-28). Irep-28 is identified as the DNA-binding HU homologue HupB protein (hupB [Rv2986c]). Antibodies to this protein were detected in sera from tuberculosis patients. The location of the protein in the cell wall makes it a potential drug target. Copyright © 2006, American Society for Microbiology. All Rights Reserved. | |
| dc.identifier.citation | Clinical and Vaccine Immunology. v.13(10) | |
| dc.identifier.issn | 15566811 | |
| dc.identifier.uri | 10.1128/CVI.00125-06 | |
| dc.identifier.uri | https://journals.asm.org/doi/10.1128/CVI.00125-06 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/3690 | |
| dc.title | Identification and characterization of a major cell wall-associated iron-regulated envelope protein (Irep-28) in Mycobacterium tuberculosis | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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