Synthesis of the 1,3-Dioxolane Ring System of the Trichothecenes Sambucinol and Sporol via a Stereoselective Claisen Rearrangement
Synthesis of the 1,3-Dioxolane Ring System of the Trichothecenes Sambucinol and Sporol via a Stereoselective Claisen Rearrangement
| dc.contributor.author | Ziegler, Frederick E. | |
| dc.contributor.author | Nangia, Ashwini | |
| dc.contributor.author | Schulte, Gayle | |
| dc.date.accessioned | 2022-03-27T09:36:23Z | |
| dc.date.available | 2022-03-27T09:36:23Z | |
| dc.date.issued | 1987-06-01 | |
| dc.description.abstract | The major stereoisomer from the Claisen rearrangement of allyl vinyl ether 10 was shown to be keto nitrile 12 by an X-ray crystallographic analysis on the derived hydroxy nitrile 15. In a similar fashion, allyl vinyl ether 22 produced keto nitrile 23a. This substance was converted into hydroxymethyl ketal 25, which bears the 1,3-dioxolane ring system present in sambucinol 1 and sporol 2. © 1987, American Chemical Society. All rights reserved. | |
| dc.identifier.citation | Journal of the American Chemical Society. v.109(13) | |
| dc.identifier.issn | 00027863 | |
| dc.identifier.uri | 10.1021/ja00247a026 | |
| dc.identifier.uri | https://pubs.acs.org/doi/abs/10.1021/ja00247a026 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/13106 | |
| dc.title | Synthesis of the 1,3-Dioxolane Ring System of the Trichothecenes Sambucinol and Sporol via a Stereoselective Claisen Rearrangement | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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