Highly diastereoselective synthesis of tertiary alcohols via intramolecular Baylis-Hillman reaction using less reactive acrylamides as activated alkenes and ketones as electrophiles

dc.contributor.author	Basavaiah, Deevi
dc.contributor.author	Reddy, Guddeti Chandrashekar
dc.contributor.author	Lingaiah, Balthu
dc.contributor.author	Naganaboina, Ram Tilak
dc.date.accessioned	2022-03-27T09:00:47Z
dc.date.available	2022-03-27T09:00:47Z
dc.date.issued	2017-01-01
dc.description.abstract	A simple and convenient protocol for highly diastereoselective intramolecular Baylis-Hillman (IBH) reaction of substrates containing less reactive acrylamides as activated alkene and ketones with α-chiral center (racemic) as electrophile components, thus producing α-methylene-γ-lactam frameworks having β-tertiary alcoholic functional group, has been developed.
dc.identifier.citation	Tetrahedron. v.73(7)
dc.identifier.issn	00404020
dc.identifier.uri	10.1016/j.tet.2016.12.069
dc.identifier.uri	https://www.sciencedirect.com/science/article/abs/pii/S0040402016313667
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/12264
dc.subject	Diastereoselective synthesis
dc.subject	Intramolecular Baylis-Hillman reaction
dc.subject	Tertiary alcohols
dc.subject	α-Methylene-γ-lactam framework
dc.title	Highly diastereoselective synthesis of tertiary alcohols via intramolecular Baylis-Hillman reaction using less reactive acrylamides as activated alkenes and ketones as electrophiles
dc.type	Journal. Article
dspace.entity.type

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