Expeditious synthetic route to B-ring functionalised 2-oxa-steroids: Synthesis of 17-ethylenedioxy-6α-hydroxy-2-oxa-4-androsten-3-one as key synthon

dc.contributor.author Nangia, Ashwini
dc.contributor.author Anthony, A.
dc.date.accessioned 2022-03-27T09:34:56Z
dc.date.available 2022-03-27T09:34:56Z
dc.date.issued 1997-12-01
dc.description.abstract The easily prepared 17-ethylenedioxy-4-androsten-3,6-dione 8 is transformed to 17-ethylenedioxy-6α-hydroxy-2-oxa-4-androsten-3-one 15 in a few steps with complete stereo- and regio-control. The hydroxylactone 15 provides an easy entry to B-ring functionalised 2-oxa-androgens for evaluation as potential aromatase inhibitors and anabolic agents.
dc.identifier.citation Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry. v.36(12)
dc.identifier.issn 03764699
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/13078
dc.title Expeditious synthetic route to B-ring functionalised 2-oxa-steroids: Synthesis of 17-ethylenedioxy-6α-hydroxy-2-oxa-4-androsten-3-one as key synthon
dc.type Journal. Article
dspace.entity.type
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