Resolution of C < inf > 2 < /inf > -symmetric 2,3-diphenylbutane-1,4-diol and purification of diastereomeric 1,4-diphenylbutane-1,4-diol using (S)-proline and boric acid
Resolution of C < inf > 2 < /inf > -symmetric 2,3-diphenylbutane-1,4-diol and purification of diastereomeric 1,4-diphenylbutane-1,4-diol using (S)-proline and boric acid
| dc.contributor.author | Periasamy, Mariappan | |
| dc.contributor.author | Rao, Vutukuri Dharma | |
| dc.contributor.author | Seenivasaperumal, Muthu | |
| dc.date.accessioned | 2022-03-27T09:09:41Z | |
| dc.date.available | 2022-03-27T09:09:41Z | |
| dc.date.issued | 2001-07-30 | |
| dc.description.abstract | Racemic 2,3-diphenylbutane-1,4-diol (±)-1 is resolved to obtain the corresponding (R,R)-isomer in 98% e.e. through reaction with (S)-proline and boric acid. Partially resolved (R,R)-(-)-1 and (S,S)-(+)-1 have been enriched to obtain samples of 95 and 97% e.e. through reaction with (S)-proline and boric acid. Diastereomeric 1,4-diphenylbutane-1,4-diol 2 has been purified to obtain the (R,R)-isomer in 98% e.e. using (S)-proline and boric acid. © 2001 Elsevier Science Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron Asymmetry. v.12(13) | |
| dc.identifier.issn | 09574166 | |
| dc.identifier.uri | 10.1016/S0957-4166(01)00329-9 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0957416601003299 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12513 | |
| dc.title | Resolution of C < inf > 2 < /inf > -symmetric 2,3-diphenylbutane-1,4-diol and purification of diastereomeric 1,4-diphenylbutane-1,4-diol using (S)-proline and boric acid | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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