Base-promoted one-pot sequential phosphite addition and 5- exo -dig cyclization of enynals: A facile route to trisubstituted furans

dc.contributor.author	Uravakilli, Anasuyamma
dc.contributor.author	Kotikalapudi, Ramesh
dc.contributor.author	Kumara Swamy, K. C.
dc.date.accessioned	2022-03-27T09:50:14Z
dc.date.available	2022-03-27T09:50:14Z
dc.date.issued	2014-01-01
dc.description.abstract	An easy route for the synthesis of trisubstituted furans has been demonstrated. One-pot sequential phosphite (H-phosphonate) addition to alkynylaldehydes (enynals) promoted by tripotassium phosphate leads to trisubstituted furans (phosphono-furans) via 5-exo-dig cyclization of the phosphono-alkynol intermediates. In contrast, in the presence of silver(I) tetrafluoroborate, the reaction using the same substrates leads to a diene product. © Georg Thieme Verlag Stuttgart, New York.
dc.identifier.citation	Synthesis (Germany). v.46(9)
dc.identifier.issn	00397881
dc.identifier.uri	10.1055/s-0033-1340865
dc.identifier.uri	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1340865
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/13356
dc.subject	cyclization
dc.subject	enynals
dc.subject	furans
dc.subject	isomerization
dc.subject	nucleophilic addition
dc.subject	phosphorus
dc.title	Base-promoted one-pot sequential phosphite addition and 5- exo -dig cyclization of enynals: A facile route to trisubstituted furans
dc.type	Journal. Article
dspace.entity.type

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