(2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane: A novel chiral source for borane-mediated catalytic chiral reductions
(2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane: A novel chiral source for borane-mediated catalytic chiral reductions
| dc.contributor.author | Basavaiah, Deevi | |
| dc.contributor.author | Jayapal Reddy, Gone | |
| dc.contributor.author | Chandrashekar, Vanampally | |
| dc.date.accessioned | 2022-03-27T09:02:47Z | |
| dc.date.available | 2022-03-27T09:02:47Z | |
| dc.date.issued | 2002-06-21 | |
| dc.description.abstract | (2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane has been successfully employed as a chiral catalytic source for the borane mediated asymmetric reductions of prochiral α-halo ketones to provide the desired (S)-secondary alcohols in 81-91% enantiomeric purities, thus for the first time demonstrating the potential of the N-P(=O)Cl structural framework to generate a recoverable, reusable and air stable catalyst for the asymmetric reduction processes. © 2002 Elsevier Science Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron Asymmetry. v.13(11) | |
| dc.identifier.issn | 09574166 | |
| dc.identifier.uri | 10.1016/S0957-4166(02)00263-X | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S095741660200263X | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12324 | |
| dc.title | (2S,5S)-1,3-Diaza-2-phospha-2-oxo-2-chloro-3-phenylbicyclo[3.3.0]octane: A novel chiral source for borane-mediated catalytic chiral reductions | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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