Copper-catalyzed N-arylation of amines/amides in poly(ethylene glycol) as recyclable solvent medium
Copper-catalyzed N-arylation of amines/amides in poly(ethylene glycol) as recyclable solvent medium
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Date
2006-03-01
Authors
Chandrasekhar, Srivari
Sultana, S. Shameem
Yaragorla, Srinivasa Rao
Reddy, N. Ramakrishna
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Abstract
The Buchwald N-arylation of amines and amides is achieved efficiently in PEG (400 Daltons) as solvent medium. The solvent and catalyst recyclability is studied. Interestingly amides underwent N-arylation with better yields. © Georg Thieme Verlag Stuttgart.
Description
Keywords
Copper iodide,
N-arylation,
Poly(ethylene glycol),
Reusability
Citation
Synthesis