Gene regulatory networks that orchestrate the development of B lymphocyte precursors

dc.contributor.author	Singh, Harinder
dc.contributor.author	Pongubala, Jagan M.R.
dc.contributor.author	Medina, Kay L.
dc.date.accessioned	2022-03-27T00:59:27Z
dc.date.available	2022-03-27T00:59:27Z
dc.date.issued	2007-01-01
dc.description.abstract	The B cell developmental pathway represents a leading model within the hematopoietc system for the analysis of gene regulatory networks, which orchestrate cell fate specification and commitment. Considerable progress is being made in the characterization of regulatory components that comprise such networks and examining their connectivity. These components include the cytokine receptors Flk2 and IL-7R as well as the transcription factors PU.1, Ikaros, E2A, EBF and Pax-5. We review recent experimental evidence concerning the molecular functions of these regulatory components and attempt to connect them in sequentially acting and inter-dependent regulatory modules. © 2007 Springer Science+Business Media, LLC.
dc.identifier.citation	Advances in Experimental Medicine and Biology. v.596
dc.identifier.issn	00652598
dc.identifier.uri	10.1007/0-387-46530-8_5
dc.identifier.uri	http://link.springer.com/10.1007/0-387-46530-8_5
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/3714
dc.title	Gene regulatory networks that orchestrate the development of B lymphocyte precursors
dc.type	Book Series. Conference Paper
dspace.entity.type

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