A calcium catalysed regioselective (5-exo dig) tandem process for the synthesis of fully substituted furans
A calcium catalysed regioselective (5-exo dig) tandem process for the synthesis of fully substituted furans
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Date
2016-01-01
Authors
Yaragorla, Srinivasarao
Dada, Ravikrishna
Pareek, Abhishek
Singh, Garima
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Abstract
An efficient and highly regio-selective synthesis of fused & substituted furans has been described using Ca(OTf)2 as the catalyst. This tandem process involves alkylation, 5-exo dig cyclisation and isomerization to furnish densely substituted furans under solvent free conditions. A case study of regioselectivity has been demonstrated.
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RSC Advances. v.6(34)