Sulfoximine assisted Pd(II)-catalyzed bromination and chlorination of primary β-C(sp < sup > 3 < /sup > )-H bond
Sulfoximine assisted Pd(II)-catalyzed bromination and chlorination of primary β-C(sp < sup > 3 < /sup > )-H bond
| dc.contributor.author | Rit, Raja K. | |
| dc.contributor.author | Yadav, M. Ramu | |
| dc.contributor.author | Ghosh, Koushik | |
| dc.contributor.author | Shankar, Majji | |
| dc.contributor.author | Sahoo, Akhila K. | |
| dc.date.accessioned | 2022-03-27T08:33:52Z | |
| dc.date.available | 2022-03-27T08:33:52Z | |
| dc.date.issued | 2014-10-17 | |
| dc.description.abstract | S-Methyl-S-2-pyridyl-sulfoximine (MPyS) directed bromination and chlorination of the 1°-β-C(sp3)-H bond of MPyS-N-amides is realized under the influence of N-Br/Cl-phthalimides and a Pd(II)-catalyst. The sequential halogenation and acetoxylation of α-dimethyl MPyS-N-amides constructs highly functionalized α-trisubstituted aliphatic acid derivatives. The MPyS directing group is cleaved from the halogenated products and recovered. (Chemical Equation Presented). | |
| dc.identifier.citation | Organic Letters. v.16(20) | |
| dc.identifier.issn | 15237060 | |
| dc.identifier.uri | 10.1021/ol502337b | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/ol502337b | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/10815 | |
| dc.title | Sulfoximine assisted Pd(II)-catalyzed bromination and chlorination of primary β-C(sp < sup > 3 < /sup > )-H bond | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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