Enantioselective hydrolysis of 2,2-disubstituted oxiranes mediated by microsomal epoxide hydrolase

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Date
1995-11-01
Authors
Basavaiah, Deevi
Raju, Sarikonda Bhaskar
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Abstract
2-Aryl-2-methyloxiranes are enantioselectively hydrolyzed with microsomal epoxide hydrolase from pig liver to provide 1,2-diols containing a tertiary benzylic alcohol stereogenic centre upto 34% enantiomeric purities. © 1995, Taylor & Francis Group, LLC. All rights reserved.
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Synthetic Communications. v.25(21)