Synthesis of new derivatives from a Tröger base via exchange of the methano bridge with carbonyl compounds
Synthesis of new derivatives from a Tröger base via exchange of the methano bridge with carbonyl compounds
| dc.contributor.author | Periasamy, Mariappan | |
| dc.contributor.author | Suresh, Sundaram | |
| dc.contributor.author | Satishkumar, Sakilam | |
| dc.date.accessioned | 2022-03-27T09:07:23Z | |
| dc.date.available | 2022-03-27T09:07:23Z | |
| dc.date.issued | 2012-01-31 | |
| dc.description.abstract | A simple one-pot method has been developed for the preparation of new Tröger base derivatives by an exchange reaction with the methano bridge of rac-Tröger base derivatives with carbonyl compounds in the presence of TiCl 4 or POCl 3. The use of chiral (S,S)-N,N-bis(α- methylbenzyl)formamide as a carbonyl compound gave the corresponding methano Tröger base derivatives with the diastereomeric ratios of up to 77:23. © 2012 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Tetrahedron Asymmetry. v.23(2) | |
| dc.identifier.issn | 09574166 | |
| dc.identifier.uri | 10.1016/j.tetasy.2012.01.009 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0957416612000596 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12451 | |
| dc.title | Synthesis of new derivatives from a Tröger base via exchange of the methano bridge with carbonyl compounds | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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