Access to cyclobutene-fused azepines through au-catalyzed cycloisomerization of stable alkyne tethered ketene N,N -acetals
Access to cyclobutene-fused azepines through au-catalyzed cycloisomerization of stable alkyne tethered ketene N,N -acetals
| dc.contributor.author | Nayak, Sanatan | |
| dc.contributor.author | Ghosh, Nayan | |
| dc.contributor.author | Sahoo, Akhila K. | |
| dc.date.accessioned | 2022-03-27T08:34:04Z | |
| dc.date.available | 2022-03-27T08:34:04Z | |
| dc.date.issued | 2014-06-06 | |
| dc.description.abstract | A base promoted reaction between N-protected propargyl amines and 3-bromopropiolate readily provides an array of novel stable alkyne-tethered ketene N,N-acetals in good yields. A wide range of structurally complex cyclobutene-fused azepine heterocycles are synthesized through the gold-catalyzed intramolecular cycloisomerization of ketene N,N-acetals for the first time. A plausible reaction pathway is deduced on the basis of the 1H NMR studies. © 2014 American Chemical Society. | |
| dc.identifier.citation | Organic Letters. v.16(11) | |
| dc.identifier.issn | 15237060 | |
| dc.identifier.uri | 10.1021/ol501125r | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/ol501125r | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/10860 | |
| dc.title | Access to cyclobutene-fused azepines through au-catalyzed cycloisomerization of stable alkyne tethered ketene N,N -acetals | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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