Microwave-assisted one-pot synthesis of pyrazolo[3,4- b]indoles and new isoxazolo[5,4- b]indoles via copper-catalyzed intramolecular C-N/C-O bond formation
Microwave-assisted one-pot synthesis of pyrazolo[3,4- b]indoles and new isoxazolo[5,4- b]indoles via copper-catalyzed intramolecular C-N/C-O bond formation
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Date
2011-10-21
Authors
Kumar, Arepalli Sateesh
Rao, P. V.Amulya
Nagarajan, Rajagopal
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Abstract
A facile one-pot, two-step synthesis of highly substituted pyrazolo[3,4-b]indoles and isoxazolo[5,4-b]indoles was developed via microwave-assisted, copper-catalyzed intramolecular heterocyclization (involving C-N/C-O bond formation) from 3-acetyl-2-chloroindoles in good to excellent yields. © Georg Thieme Verlag Stuttgart. New York.
Description
Keywords
3-acyl-2-chloroindoles,
copper catalysis,
intramolecular hetero-arylation,
isoxazolo[5,4- b]indoles,
pyrazolo[3,4- b]indoles
Citation
Synthesis