Efficient resolution of (±)-trans-2,3-diphenylpiperazine using (1S)-(+)10-camphorsulfonic acid and enrichment of enantiomeric purity of non-racemic 2,3-diphenylpiperazine using different achiral acids
Efficient resolution of (±)-trans-2,3-diphenylpiperazine using (1S)-(+)10-camphorsulfonic acid and enrichment of enantiomeric purity of non-racemic 2,3-diphenylpiperazine using different achiral acids
| dc.contributor.author | Vairaprakash, Pothiappan | |
| dc.contributor.author | Periasamy, Mariappan | |
| dc.date.accessioned | 2022-03-27T09:08:08Z | |
| dc.date.available | 2022-03-27T09:08:08Z | |
| dc.date.issued | 2008-01-01 | |
| dc.description.abstract | Enantiomerically pure (R,R)-(+)-2,3-diphenylpiperazine with 98% ee was obtained by resolution of the corresponding racemic mixture using (15)-(+)-10-camphorsulfonic acid. The partially resolved enriched sample of (S,S)-(-)-2,3-diphenylpiperazine with 73% ee was purified to obtain samples of 97% ee using different achiral acids via the preparation of either homochiral or heterochiral hydrogen bonded aggregates. © Indian Academy of Sciences. | |
| dc.identifier.citation | Journal of Chemical Sciences. v.120(1) | |
| dc.identifier.issn | 02534134 | |
| dc.identifier.uri | 10.1007/s12039-008-0020-5 | |
| dc.identifier.uri | http://link.springer.com/10.1007/s12039-008-0020-5 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12471 | |
| dc.subject | 2,3-diphenylpiperazine | |
| dc.subject | Camphorsulfonic acid | |
| dc.subject | Heterochiral aggregates | |
| dc.subject | Homochiral aggregates | |
| dc.subject | Resolution | |
| dc.title | Efficient resolution of (±)-trans-2,3-diphenylpiperazine using (1S)-(+)10-camphorsulfonic acid and enrichment of enantiomeric purity of non-racemic 2,3-diphenylpiperazine using different achiral acids | |
| dc.type | Journal. Article | |
| dspace.entity.type |
Files
License bundle
1 - 1 of 1