Organocatalytic Asymmetric Formal [3+3]-Cycloaddition to Access 2,3-Diazaspiro[4.5]deca-3,6-dien-1-ones

dc.contributor.author	Krishna, A. Vamshi
dc.contributor.author	Reddy, G. Surendra
dc.contributor.author	Gorachand, B.
dc.contributor.author	Ramachary, Dhevalapally B.
dc.date.accessioned	2022-03-27T09:36:45Z
dc.date.available	2022-03-27T09:36:45Z
dc.date.issued	2020-11-15
dc.description.abstract	Medicinally important 2,3-diazaspiro[4.5]deca-3,6-dien-1-ones having vicinal quaternary centers were constructed in very good yields with high enantio- and diastereoselectivities through an organocatalytic formal [3+3]-cycloaddition or domino Michael/aldol reactions, which is driven by the double sequence of in situ isoaromatization and dearomatization steps from the α-arylidene pyrazolinones and (E)-alkyl 2-oxo-4-arylbut-3-enoates.
dc.identifier.citation	European Journal of Organic Chemistry. v.2020(42)
dc.identifier.issn	1434193X
dc.identifier.uri	10.1002/ejoc.202001175
dc.identifier.uri	https://onlinelibrary.wiley.com/doi/10.1002/ejoc.202001175
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/13113
dc.subject	Dearomatization
dc.subject	Domino reactions
dc.subject	Isoaromatization
dc.subject	Organocatalysis
dc.subject	[3+3]-Cycloaddition
dc.title	Organocatalytic Asymmetric Formal [3+3]-Cycloaddition to Access 2,3-Diazaspiro[4.5]deca-3,6-dien-1-ones
dc.type	Journal. Article
dspace.entity.type

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