PEG-SO <inf>3</inf>H catalyzed synthesis and cytotoxicity of α-aminophosphonates
PEG-SO <inf>3</inf>H catalyzed synthesis and cytotoxicity of α-aminophosphonates
| dc.contributor.author | Reddy, C. Bhupendra | |
| dc.contributor.author | Kumar, K. Suresh | |
| dc.contributor.author | Kumar, M. Anil | |
| dc.contributor.author | Narayana Reddy, M. Veera | |
| dc.contributor.author | Krishna, B. Satheesh | |
| dc.contributor.author | Naveen, M. | |
| dc.contributor.author | Arunasree, M. K. | |
| dc.contributor.author | Reddy, C. Suresh | |
| dc.contributor.author | Raju, C. Naga | |
| dc.contributor.author | Reddy, C. Devendranath | |
| dc.date.accessioned | 2022-03-27T01:02:18Z | |
| dc.date.available | 2022-03-27T01:02:18Z | |
| dc.date.issued | 2012-01-01 | |
| dc.description.abstract | One pot three-component PEG-SO 3H catalyzed reaction of 4-(Pyridin-4-yl)benzaldehyde and triethyl phosphite with various primary amines afforded α-aminophosphonates with high yields by the Kabachnik-Field's reaction. These new structurally diversified set of α-aminophosphonates (4a-j) were evaluated for their anti-tumor activity on human chronic myeloid leukemia cells (K 562), human colon carcinoma cells (Colo 205) along with non-cancerous human embryonic kidney cells (HEK 293). They showed moderate activity on both cancerous cells and non-cancerous cells. © 2011 Elsevier Masson SAS. All rights reserved. | |
| dc.identifier.citation | European Journal of Medicinal Chemistry. v.47(1) | |
| dc.identifier.issn | 02235234 | |
| dc.identifier.uri | 10.1016/j.ejmech.2011.11.026 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0223523411008488 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/3946 | |
| dc.subject | 4-(Pyridin-4-yl)benzaldehyde | |
| dc.subject | Human chronic myeloid leukemia cells (K 562) | |
| dc.subject | Human colon carcinoma cells (Colo 205) | |
| dc.subject | Human embryonic kidney cells (HEK 293) | |
| dc.subject | Poly ethylene glycol sulfonic acid (PEG-SO H) 3 | |
| dc.title | PEG-SO <inf>3</inf>H catalyzed synthesis and cytotoxicity of α-aminophosphonates | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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