Synthesis and biological evaluation of new 4β-anilino- and 4β-imido-substituted podophyllotoxin congeners
Synthesis and biological evaluation of new 4β-anilino- and 4β-imido-substituted podophyllotoxin congeners
| dc.contributor.author | Kamal, Ahmed | |
| dc.contributor.author | Gayatri, N. Lakshmi | |
| dc.contributor.author | Rajasekhar Reddy, D. | |
| dc.contributor.author | Murali Mohan Reddy, P. S. | |
| dc.contributor.author | Arifuddin, M. | |
| dc.contributor.author | Dastidar, Sunanda G. | |
| dc.contributor.author | Kondapi, Anand K. | |
| dc.contributor.author | Rajkumar, M. | |
| dc.date.accessioned | 2022-03-27T05:16:18Z | |
| dc.date.available | 2022-03-27T05:16:18Z | |
| dc.date.issued | 2005-11-15 | |
| dc.description.abstract | A series of C-4-anilino- and C-4-imido-substituted new podophyllotoxin congeners have been designed, synthesized, and evaluated for their cytotoxicity and DNA topoisomerase-II (topo-II) inhibition potential. Some of these compounds have exhibited promising in vitro anticancer and topo-II inhibition activity. © 2005 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Bioorganic and Medicinal Chemistry. v.13(22) | |
| dc.identifier.issn | 09680896 | |
| dc.identifier.uri | 10.1016/j.bmc.2005.06.032 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0968089605005705 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/7592 | |
| dc.subject | DNA topoisomerase-II | |
| dc.subject | Etoposide | |
| dc.subject | Podophyllotoxin | |
| dc.subject | Substituted 2-aminobenzophenone | |
| dc.title | Synthesis and biological evaluation of new 4β-anilino- and 4β-imido-substituted podophyllotoxin congeners | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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