Highly soluble olanzapinium maleate crystalline salts
Highly soluble olanzapinium maleate crystalline salts
| dc.contributor.author | Thakuria, Ranjit | |
| dc.contributor.author | Nangia, Ashwini | |
| dc.date.accessioned | 2022-03-27T09:27:27Z | |
| dc.date.available | 2022-03-27T09:27:27Z | |
| dc.date.issued | 2011-03-21 | |
| dc.description.abstract | Olanzapinium monomaleate and dimaleate salts (OLNH+ MA - 1:1 and OLN2H+ 2MA- 1:2) of crystalline and amorphous states were prepared. The crystalline salts exhibit significantly higher solubility (225-550 times) compared to the almost insoluble free base drug Olanzapine (43 mg L-1). The faster dissolution rate of the 1:2 salt compared to 1:1 is explained by their crystal structure analysis. © 2011 The Royal Society of Chemistry. | |
| dc.identifier.citation | CrystEngComm. v.13(6) | |
| dc.identifier.issn | 14668033 | |
| dc.identifier.uri | 10.1039/c0ce00787k | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=c0ce00787k | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12928 | |
| dc.title | Highly soluble olanzapinium maleate crystalline salts | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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