High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations
High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations
| dc.contributor.author | Ramachary, Dhevalapally B. | |
| dc.contributor.author | Narayana, Vidadala V. | |
| dc.contributor.author | Prasad, M. Shiva | |
| dc.contributor.author | Ramakumar, Kinthada | |
| dc.date.accessioned | 2022-03-27T09:41:05Z | |
| dc.date.available | 2022-03-27T09:41:05Z | |
| dc.date.issued | 2009-09-25 | |
| dc.description.abstract | An efficient amine-/ruthenium-catalyzed three-step process for the synthesis of Nefopam analogues was achieved through combinations of cascade enamine amination/iso-aromatization/allylation and diene or enyne metathesis as key steps starting from functionalized Hagemann's esters. In this communication, we discovered the application of ruthenium-catalysis on olefins containing free amines without in situ formation of salts. © 2009 The Royal Society of Chemistry. | |
| dc.identifier.citation | Organic and Biomolecular Chemistry. v.7(17) | |
| dc.identifier.issn | 14770520 | |
| dc.identifier.uri | 10.1039/b910397j | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=b910397j | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/13194 | |
| dc.title | High-yielding synthesis of Nefopam analogues (functionalized benzoxazocines) by sequential one-pot cascade operations | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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