A facile tandem construction of C-O and C-C bonds: A novel one-pot transformation of Baylis-Hillman adducts into 2-benzoxepines
A facile tandem construction of C-O and C-C bonds: A novel one-pot transformation of Baylis-Hillman adducts into 2-benzoxepines
No Thumbnail Available
Date
2004-04-05
Authors
Basavaiah, Deevi
Sharada, Duddu S.
Veerendhar, Ainelly
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
A facile and one-pot synthesis of 2-benzoxepines, from Baylis-Hillman adducts that is, alkyl 3-aryl-3-hydroxy-2-methylenepropanoates, via treatment with HCHO in the presence of concd H2SO4, involving tandem construction of C-O and C-C bonds via Prins-type and Friedel-Crafts reactions, is described. © 2004 Elsevier Ltd. All rights reserved.
Description
Keywords
2-Benzoxepines,
Baylis-Hillman chemistry,
Friedel-Crafts reaction,
Para-Formaldehyde,
Prins-type reaction
Citation
Tetrahedron Letters. v.45(15)