The Baylis-Hillman chemistry in aqueous media: A convenient synthesis of 2-methylenealkanoates and alkanenitriles
The Baylis-Hillman chemistry in aqueous media: A convenient synthesis of 2-methylenealkanoates and alkanenitriles
| dc.contributor.author | Basavaiah, Deevi | |
| dc.contributor.author | Kumaragurubaran, Nagaswamy | |
| dc.date.accessioned | 2022-03-27T09:03:16Z | |
| dc.date.available | 2022-03-27T09:03:16Z | |
| dc.date.issued | 2001-01-15 | |
| dc.description.abstract | A convenient, general and efficient synthesis of 2-methylenealkanoates and alkanenitriles is accomplished via the regioselective nucleophilic (SN2′) addition of hydride ion from NaBH4 to (2Z)-2-(bromomethyl)alk-2-enoates and 2-(bromomethyl)alk-2-enenitriles respectively in the presence of DABCO in environment friendly aqueous media. Synthesis of two hypoglycemic agents is also described. © 2001 Elsevier Science Ltd. | |
| dc.identifier.citation | Tetrahedron Letters. v.42(3) | |
| dc.identifier.issn | 00404039 | |
| dc.identifier.uri | 10.1016/S0040-4039(00)01967-5 | |
| dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0040403900019675 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/12338 | |
| dc.subject | 2-Methylenealkanoates | |
| dc.subject | Alkanenitriles | |
| dc.subject | Baylis-Hillman chemistry | |
| dc.subject | Regioselectivity | |
| dc.title | The Baylis-Hillman chemistry in aqueous media: A convenient synthesis of 2-methylenealkanoates and alkanenitriles | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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