A green synthesis of unsymmetrical 9-arylxanthenes in a one-pot cascade benzylation/annulation/dehydration strategy

Simple item page
dc.contributor.author Yaragorla, Srinivasarao
dc.contributor.author Saini, Pyare L.
dc.contributor.author Babu, P. Vijaya
dc.contributor.author Almansour, Abdulrahman I.
dc.contributor.author Arumugam, Natarajan
dc.date.accessioned 2022-03-27T08:49:49Z
dc.date.available 2022-03-27T08:49:49Z
dc.date.issued 2016-06-01
dc.description.abstract A green synthesis of unsymmetrical 9-arylxanthenones is described using Ca(OTf)2 in one-pot cascade benzylation, annulation and dehydration strategy starting from readily accessible π-activated carbinols. 4-Hydroxycoumarin/cyclohexane-1,3-dione required to be refluxed in water with 2-(hydroxy(phenyl)methyl)phenol derivatives in the presence of 5 mol % of Ca(OTf)2 to yield the unsymmetrical 9H-xanthenes, whereas α/β-naphthols reacted under solvent free-microwave irradiation conditions. Use of ecofriendly alkaline earth catalyst, water as the solvent, mw-irradiation, substrate scope and high yields make this methodology more amenable.
dc.identifier.citation Tetrahedron Letters. v.57(22)
dc.identifier.issn 00404039
dc.identifier.uri 10.1016/j.tetlet.2016.04.016
dc.identifier.uri https://www.sciencedirect.com/science/article/abs/pii/S0040403916303665
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/11889
dc.subject Calcium catalysis
dc.subject Green synthesis
dc.subject Heterocyclic compounds
dc.subject Microwave reaction
dc.subject Tandem process
dc.subject Unsymmetrical xanthenes
dc.title A green synthesis of unsymmetrical 9-arylxanthenes in a one-pot cascade benzylation/annulation/dehydration strategy
dc.type Journal. Article
dspace.entity.type
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Plain Text
Description:
Download
Collections
Chemistry - Publications