Synthesis of novel non-cross-linking pyrrolobenzodiazepines with remarkable DNA binding affinity and potent antitumour activity
Synthesis of novel non-cross-linking pyrrolobenzodiazepines with remarkable DNA binding affinity and potent antitumour activity
| dc.contributor.author | Kamal, A. | |
| dc.contributor.author | Laxman, N. | |
| dc.contributor.author | Ramesh, G. | |
| dc.contributor.author | Neelima, K. | |
| dc.contributor.author | Kondapi, A. K. | |
| dc.date.accessioned | 2022-03-27T05:16:19Z | |
| dc.date.available | 2022-03-27T05:16:19Z | |
| dc.date.issued | 2001-03-07 | |
| dc.description.abstract | Mixed imine-amide pyrrolobenzodiazepine dimers have been prepared which exhibit potent antitumour activity and have significant DNA binding affinity; one of them, 1c, has been shown to cause a remarkable rise in the melting temperature of calf thymus DNA. | |
| dc.identifier.citation | Chemical Communications | |
| dc.identifier.issn | 13597345 | |
| dc.identifier.uri | 10.1039/b009195m | |
| dc.identifier.uri | http://xlink.rsc.org/?DOI=b009195m | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/7604 | |
| dc.title | Synthesis of novel non-cross-linking pyrrolobenzodiazepines with remarkable DNA binding affinity and potent antitumour activity | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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