Iodo-Cycloisomerization of Aryl(indol-3-yl)methane-Tethered Propargyl Alcohols to 3-Iodocarbazoles via Selective 1,2-Alkyl Migration
Iodo-Cycloisomerization of Aryl(indol-3-yl)methane-Tethered Propargyl Alcohols to 3-Iodocarbazoles via Selective 1,2-Alkyl Migration
| dc.contributor.author | Yaragorla, Srinivasarao | |
| dc.contributor.author | Bag, Debojyoti | |
| dc.contributor.author | Dada, Ravikrishna | |
| dc.contributor.author | Jose, K. V.Jovan | |
| dc.date.accessioned | 2022-03-27T08:49:27Z | |
| dc.date.available | 2022-03-27T08:49:27Z | |
| dc.date.issued | 2018-11-07 | |
| dc.description.abstract | Herein, we disclose the first report on iodo-cycloisomerization of 1-(indol-3-yl)-1-arylbut-3-yn-2-ols to form 3-iodocarbazoles. The synthesis proceeds through a cascade 5-endo-spirocyclization, followed by selective 1,2-alkyl migration. This method governs the green synthesis principles such as open-flask reaction, AcOEt as the solvent, rt reaction with short time, use of iodine, and broad substrate scope with atom and step economy. | |
| dc.identifier.citation | ACS Omega. v.3(11) | |
| dc.identifier.uri | 10.1021/acsomega.8b02393 | |
| dc.identifier.uri | https://pubs.acs.org/doi/10.1021/acsomega.8b02393 | |
| dc.identifier.uri | https://dspace.uohyd.ac.in/handle/1/11874 | |
| dc.title | Iodo-Cycloisomerization of Aryl(indol-3-yl)methane-Tethered Propargyl Alcohols to 3-Iodocarbazoles via Selective 1,2-Alkyl Migration | |
| dc.type | Journal. Article | |
| dspace.entity.type |
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