Alkylation of α-Oxo-Compounds through C(sp < sup > 3 < /sup > )-H Functionalization of 2-Methyl Quinolines Under Catalyst- and Solvent-Free Conditions

dc.contributor.author	Rao, Yadavalli Subba
dc.contributor.author	Latha, Dandugula Sneha
dc.contributor.author	Devunuri, Nagaraju
dc.contributor.author	Almansour, Abdulrahman I.
dc.contributor.author	Arumugam, Natarajan
dc.contributor.author	Yaragorla, Srinivasarao
dc.date.accessioned	2022-03-27T08:49:07Z
dc.date.available	2022-03-27T08:49:07Z
dc.date.issued	2020-07-23
dc.description.abstract	Highly facile approach of chemoselective alkylation of α-oxo compounds such as α-keto amides, α-keto esters, isatins, and cyclic-α-diketones is developed through C(sp3)-H functionalization of 2-methyl quinolines under solvent and catalyst-free conditions. Further, we complemented the efficacy of this green synthetic protocol by demonstrating the broad substrate diversity, gram-scale synthesis, and new synthetic transformations of the obtained products.
dc.identifier.citation	European Journal of Organic Chemistry. v.2020(27)
dc.identifier.issn	1434193X
dc.identifier.uri	10.1002/ejoc.202000511
dc.identifier.uri	https://onlinelibrary.wiley.com/doi/10.1002/ejoc.202000511
dc.identifier.uri	https://dspace.uohyd.ac.in/handle/1/11861
dc.subject	Alkylation Carbonyl compounds C–H activation Heterocycles Synthetic methods
dc.title	Alkylation of α-Oxo-Compounds through C(sp < sup > 3 < /sup > )-H Functionalization of 2-Methyl Quinolines Under Catalyst- and Solvent-Free Conditions
dc.type	Journal. Article
dspace.entity.type

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